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Effect of Pullulan Nanoparticle Surface Charges on HSA Complexation and Drug Release Behavior of HSA-Bound Nanoparticles

Nanoparticle (NP) compositions such as hydrophobicity and surface charge are vital to determine the presence and amount of human serum albumin (HSA) binding. The HSA binding influences drug release, biocompatibility, biodistribution, and intercellular trafficking of nanoparticles (NPs). Here, we pre...

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Detalles Bibliográficos
Autores principales: Tao, Xiaojun, Zhang, Qiufang, Ling, Kai, Chen, Yicun, Yang, Wenzhi, Gao, Fenfei, Shi, Ganggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498137/
https://www.ncbi.nlm.nih.gov/pubmed/23166632
http://dx.doi.org/10.1371/journal.pone.0049304