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Identification of Novel Translational Urinary Biomarkers for Acetaminophen-Induced Acute Liver Injury Using Proteomic Profiling in Mice

Drug-induced liver injury (DILI) is the leading cause of acute liver failure. Currently, no adequate predictive biomarkers for DILI are available. This study describes a translational approach using proteomic profiling for the identification of urinary proteins related to acute liver injury induced...

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Detalles Bibliográficos
Autores principales: van Swelm, Rachel P. L., Laarakkers, Coby M. M., van der Kuur, Ellen C., Morava-Kozicz, Eva, Wevers, Ron A., Augustijn, Kevin D., Touw, Daan J., Sandel, Maro H., Masereeuw, Rosalinde, Russel, Frans G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498140/
https://www.ncbi.nlm.nih.gov/pubmed/23166697
http://dx.doi.org/10.1371/journal.pone.0049524