A Simplified Method for the Efficient Refolding and Purification of Recombinant Human GM-CSF

Human granulocyte macrophage colony-stimulating factor (hGM-CSF) is a haematopoietic growth factor and proinflammatory cytokine. Recombinant hGM-CSF is important not only as a research tool but also as a biotherapeutic. However, rhGM-CSF expressed in E. coli is known to form inclusion bodies of misf...

Descripción completa

Detalles Bibliográficos
Autores principales: Thomson, Christy A., Olson, Melanie, Jackson, Linda M., Schrader, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498172/
https://www.ncbi.nlm.nih.gov/pubmed/23166789
http://dx.doi.org/10.1371/journal.pone.0049891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498172/
https://www.ncbi.nlm.nih.gov/pubmed/23166789
http://dx.doi.org/10.1371/journal.pone.0049891

Ejemplares similares