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A Simplified Method for the Efficient Refolding and Purification of Recombinant Human GM-CSF
Human granulocyte macrophage colony-stimulating factor (hGM-CSF) is a haematopoietic growth factor and proinflammatory cytokine. Recombinant hGM-CSF is important not only as a research tool but also as a biotherapeutic. However, rhGM-CSF expressed in E. coli is known to form inclusion bodies of misf...
Autores principales: | Thomson, Christy A., Olson, Melanie, Jackson, Linda M., Schrader, John W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498172/ https://www.ncbi.nlm.nih.gov/pubmed/23166789 http://dx.doi.org/10.1371/journal.pone.0049891 |
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