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Maturation and Activity of Sterol Regulatory Element Binding Protein 1 Is Inhibited by Acyl-CoA Binding Domain Containing 3

Imbalance of lipid metabolism has been linked with pathogenesis of a variety of human pathological conditions such as diabetes, obesity, cancer and neurodegeneration. Sterol regulatory element binding proteins (SREBPs) are the master transcription factors controlling the homeostasis of fatty acids a...

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Detalles Bibliográficos
Autores principales: Chen, Yong, Patel, Vishala, Bang, Sookhee, Cohen, Natalie, Millar, John, Kim, Sangwon F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498211/
https://www.ncbi.nlm.nih.gov/pubmed/23166793
http://dx.doi.org/10.1371/journal.pone.0049906