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An Enhanced Immune Response of Mclk1 (+/−) Mutant Mice Is Associated with Partial Protection from Fibrosis, Cancer and the Development of Biomarkers of Aging
The immune response is essential for survival by destroying microorganisms and pre-cancerous cells. However, inflammation, one aspect of this response, can result in short- and long-term deleterious side-effects. Mclk1 (+/−) mutant mice can be long-lived despite displaying a hair-trigger inflammator...
Autores principales: | Wang, Dantong, Wang, Ying, Argyriou, Catherine, Carrière, Audrey, Malo, Danielle, Hekimi, Siegfried |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498213/ https://www.ncbi.nlm.nih.gov/pubmed/23166727 http://dx.doi.org/10.1371/journal.pone.0049606 |
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