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Effects of a Post-Shock Injection of the Kappa Opioid Receptor Antagonist Norbinaltorphimine (norBNI) on Fear and Anxiety in Rats

Exposure of rats to footshocks leads to an enduring behavioral state involving generalized fear responses and avoidance. Recent evidence suggests that the expression of negative emotional behaviors produced by a stressor is in part mediated by dynorphin and its main receptor, the kappa opioid recept...

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Detalles Bibliográficos
Autores principales: Rogala, Benjamin, Li, Yonghui, Li, Sa, Chen, Xiaoyu, Kirouac, Gilbert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498224/
https://www.ncbi.nlm.nih.gov/pubmed/23166745
http://dx.doi.org/10.1371/journal.pone.0049669