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Effects of a Post-Shock Injection of the Kappa Opioid Receptor Antagonist Norbinaltorphimine (norBNI) on Fear and Anxiety in Rats
Exposure of rats to footshocks leads to an enduring behavioral state involving generalized fear responses and avoidance. Recent evidence suggests that the expression of negative emotional behaviors produced by a stressor is in part mediated by dynorphin and its main receptor, the kappa opioid recept...
Autores principales: | Rogala, Benjamin, Li, Yonghui, Li, Sa, Chen, Xiaoyu, Kirouac, Gilbert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498224/ https://www.ncbi.nlm.nih.gov/pubmed/23166745 http://dx.doi.org/10.1371/journal.pone.0049669 |
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