Cargando…

Transforming Growth Factor Alpha (TGFα) Regulates Granulosa Cell Tumor (GCT) Cell Proliferation and Migration through Activation of Multiple Pathways

Granulosa cell tumors (GCTs) are the most common ovarian estrogen producing tumors, leading to symptoms of excessive estrogen such as endometrial hyperplasia and endometrial adenocarcinoma. These tumors have malignant potential and often recur. The etiology of GCT is unknown. TGFα is a potent mitoge...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Cheng, Lv, Xiangmin, Jiang, Chao, Cordes, Crystal M., Fu, Lan, Lele, Subodh M., Davis, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498304/
https://www.ncbi.nlm.nih.gov/pubmed/23155381
http://dx.doi.org/10.1371/journal.pone.0048299