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Transforming Growth Factor Alpha (TGFα) Regulates Granulosa Cell Tumor (GCT) Cell Proliferation and Migration through Activation of Multiple Pathways
Granulosa cell tumors (GCTs) are the most common ovarian estrogen producing tumors, leading to symptoms of excessive estrogen such as endometrial hyperplasia and endometrial adenocarcinoma. These tumors have malignant potential and often recur. The etiology of GCT is unknown. TGFα is a potent mitoge...
Autores principales: | Wang, Cheng, Lv, Xiangmin, Jiang, Chao, Cordes, Crystal M., Fu, Lan, Lele, Subodh M., Davis, John S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498304/ https://www.ncbi.nlm.nih.gov/pubmed/23155381 http://dx.doi.org/10.1371/journal.pone.0048299 |
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