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Molecular Mechanism of SAHA on Regulation of Autophagic Cell Death in Tamoxifen-Resistant MCF-7 Breast Cancer Cells

Objective: Tamoxifen is currently used for the treatment of estrogen receptor-positive breast cancer patients, but acquired resistance to tamoxifen is a critical problem in breast cancer therapy. Suberoylanilide hydroxamic acid (SAHA) is a prototype of the newly developed HDAC inhibitor. The aim of...

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Detalles Bibliográficos
Autores principales: Lee, Young Ju, Won, A Jin, Lee, Jaewon, Jung, Jee H., Yoon, Sungpil, Lee, Byung Mu, Kim, Hyung Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498753/
https://www.ncbi.nlm.nih.gov/pubmed/23155362
http://dx.doi.org/10.7150/ijms.5011