Statistical Comparison of Carcinogenic Effects and Dose-Response Relationships in Rats and Mice for 2,4-Toluene Diamine to those Ascribed to Toluene Diisocyanate

The U.S. National Toxicology Program (NTP) conducted 2-year bioassays of commercial grade toluene diisocyanate (TDI) (80% 2,4-TDI and 20% 2,6-TDI) and 2,4-toluene diamine (TDA) and concluded that both were carcinogenic in rodents. In the TDI study, there was an unproven but likely formation of TDA e...

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Detalles Bibliográficos
Autores principales: Sielken, Robert L., Bretzlaff, Robert S., Valdez-Flores, Ciriaco, Parod, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2012
Materias:
Statistical Models and Methods Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498838/
https://www.ncbi.nlm.nih.gov/pubmed/23172986
http://dx.doi.org/10.1080/10807039.2012.722853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498838/
https://www.ncbi.nlm.nih.gov/pubmed/23172986
http://dx.doi.org/10.1080/10807039.2012.722853

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