The impact of cow's milk-mediated mTORC1-signaling in the initiation and progression of prostate cancer

Prostate cancer (PCa) is dependent on androgen receptor signaling and aberrations of the PI3K-Akt-mTORC1 pathway mediating excessive and sustained growth signaling. The nutrient-sensitive kinase mTORC1 is upregulated in nearly 100% of advanced human PCas. Oncogenic mTORC1 signaling activates key sub...

Descripción completa

Detalles Bibliográficos
Autores principales: Melnik, Bodo C, John, Swen Malte, Carrera-Bastos, Pedro, Cordain, Loren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499189/
https://www.ncbi.nlm.nih.gov/pubmed/22891897
http://dx.doi.org/10.1186/1743-7075-9-74

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499189/
https://www.ncbi.nlm.nih.gov/pubmed/22891897
http://dx.doi.org/10.1186/1743-7075-9-74

Ejemplares similares