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Strategy for eliciting antigen-specific CD8+ T cell-mediated immune response against a cryptic CTL epitope of merkel cell polyomavirus large T antigen

BACKGROUND: Merkel cell carcinoma (MCC) is a relatively new addition to the expanding category of oncovirus-induced cancers. Although still comparably rare, the number of cases has risen dramatically in recent years. Further complicating this trend is that MCC is an extremely aggressive neoplasm wit...

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Detalles Bibliográficos
Autores principales: Gomez, Bianca P, Wang, Connie, Viscidi, Raphael P, Peng, Shiwen, He, Liangmei, Wu, T-C, Hung, Chien-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499220/
https://www.ncbi.nlm.nih.gov/pubmed/23095249
http://dx.doi.org/10.1186/2045-3701-2-36