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The Origin of Minus-end Directionality and Mechanochemistry of Ncd Motors

Adaptation of molecular structure to the ligand chemistry and interaction with the cytoskeletal filament are key to understanding the mechanochemistry of molecular motors. Despite the striking structural similarity with kinesin-1, which moves towards plus-end, Ncd motors exhibit minus-end directiona...

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Detalles Bibliográficos
Autores principales: Jana, Biman, Hyeon, Changbong, Onuchic, José N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499263/
https://www.ncbi.nlm.nih.gov/pubmed/23166486
http://dx.doi.org/10.1371/journal.pcbi.1002783