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The Origin of Minus-end Directionality and Mechanochemistry of Ncd Motors
Adaptation of molecular structure to the ligand chemistry and interaction with the cytoskeletal filament are key to understanding the mechanochemistry of molecular motors. Despite the striking structural similarity with kinesin-1, which moves towards plus-end, Ncd motors exhibit minus-end directiona...
Autores principales: | Jana, Biman, Hyeon, Changbong, Onuchic, José N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499263/ https://www.ncbi.nlm.nih.gov/pubmed/23166486 http://dx.doi.org/10.1371/journal.pcbi.1002783 |
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