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Generation, characterization and structural data of chymase binding proteins based on the human Fyn kinase SH3 domain

The serine protease chymase (EC = 3.4.21.39) is expressed in the secretory granules of mast cells, which are important in allergic reactions. Fynomers, which are binding proteins derived from the Fyn SH3 domain, were generated against human chymase to produce binding partners to facilitate crystalli...

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Detalles Bibliográficos
Autores principales: Schlatter, Daniel, Brack, Simon, Banner, David W., Batey, Sarah, Benz, Jörg, Bertschinger, Julian, Huber, Walter, Joseph, Catherine, Rufer, Arne C., van der Klooster, Anita, Weber, Martin, Grabulovski, Dragan, Hennig, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499344/
https://www.ncbi.nlm.nih.gov/pubmed/22653218
http://dx.doi.org/10.4161/mabs.20452