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Generation, characterization and structural data of chymase binding proteins based on the human Fyn kinase SH3 domain
The serine protease chymase (EC = 3.4.21.39) is expressed in the secretory granules of mast cells, which are important in allergic reactions. Fynomers, which are binding proteins derived from the Fyn SH3 domain, were generated against human chymase to produce binding partners to facilitate crystalli...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499344/ https://www.ncbi.nlm.nih.gov/pubmed/22653218 http://dx.doi.org/10.4161/mabs.20452 |