Increased serum clearance of oligomannose species present on a human IgG1 molecule

The role of Fc glycans on clearance of IgG molecule has been examined by various groups in experiments where specific glycans have been enriched or the entire spectrum of glycans was studied after administration in pre-clinical or clinical pharmacokinetic (PK) studies. The overall conclusions from t...

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Detalles Bibliográficos
Autores principales: Alessandri, Leslie, Ouellette, David, Acquah, Aima, Rieser, Mathew, LeBlond, David, Saltarelli, Mary, Radziejewski, Czeslaw, Fujimori, Taro, Correia, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499345/
https://www.ncbi.nlm.nih.gov/pubmed/22669558
http://dx.doi.org/10.4161/mabs.20450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499345/
https://www.ncbi.nlm.nih.gov/pubmed/22669558
http://dx.doi.org/10.4161/mabs.20450

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