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Increased serum clearance of oligomannose species present on a human IgG1 molecule
The role of Fc glycans on clearance of IgG molecule has been examined by various groups in experiments where specific glycans have been enriched or the entire spectrum of glycans was studied after administration in pre-clinical or clinical pharmacokinetic (PK) studies. The overall conclusions from t...
Autores principales: | Alessandri, Leslie, Ouellette, David, Acquah, Aima, Rieser, Mathew, LeBlond, David, Saltarelli, Mary, Radziejewski, Czeslaw, Fujimori, Taro, Correia, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499345/ https://www.ncbi.nlm.nih.gov/pubmed/22669558 http://dx.doi.org/10.4161/mabs.20450 |
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