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Lessons from Model Organisms: Phenotypic Robustness and Missing Heritability in Complex Disease

Genetically tractable model organisms from phages to mice have taught us invaluable lessons about fundamental biological processes and disease-causing mutations. Owing to technological and computational advances, human biology and the causes of human diseases have become accessible as never before....

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Detalles Bibliográficos
Autores principales: Queitsch, Christine, Carlson, Keisha D., Girirajan, Santhosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499356/
https://www.ncbi.nlm.nih.gov/pubmed/23166511
http://dx.doi.org/10.1371/journal.pgen.1003041