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Lessons from Model Organisms: Phenotypic Robustness and Missing Heritability in Complex Disease
Genetically tractable model organisms from phages to mice have taught us invaluable lessons about fundamental biological processes and disease-causing mutations. Owing to technological and computational advances, human biology and the causes of human diseases have become accessible as never before....
Autores principales: | Queitsch, Christine, Carlson, Keisha D., Girirajan, Santhosh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499356/ https://www.ncbi.nlm.nih.gov/pubmed/23166511 http://dx.doi.org/10.1371/journal.pgen.1003041 |
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