Lamin B1 Polymorphism Influences Morphology of the Nuclear Envelope, Cell Cycle Progression, and Risk of Neural Tube Defects in Mice

Neural tube defects (NTDs), including spina bifida and anencephaly, are common birth defects whose complex multigenic causation has hampered efforts to delineate their molecular basis. The effect of putative modifier genes in determining NTD susceptibility may be investigated in mouse models, partic...

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Detalles Bibliográficos
Autores principales: De Castro, Sandra C. P., Malhas, Ashraf, Leung, Kit-Yi, Gustavsson, Peter, Vaux, David J., Copp, Andrew J., Greene, Nicholas D. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499363/
https://www.ncbi.nlm.nih.gov/pubmed/23166514
http://dx.doi.org/10.1371/journal.pgen.1003059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499363/
https://www.ncbi.nlm.nih.gov/pubmed/23166514
http://dx.doi.org/10.1371/journal.pgen.1003059

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