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Polyadenylation-Dependent Control of Long Noncoding RNA Expression by the Poly(A)-Binding Protein Nuclear 1

The poly(A)-binding protein nuclear 1 (PABPN1) is a ubiquitously expressed protein that is thought to function during mRNA poly(A) tail synthesis in the nucleus. Despite the predicted role of PABPN1 in mRNA polyadenylation, little is known about the impact of PABPN1 deficiency on human gene expressi...

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Detalles Bibliográficos
Autores principales: Beaulieu, Yves B., Kleinman, Claudia L., Landry-Voyer, Anne-Marie, Majewski, Jacek, Bachand, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499365/
https://www.ncbi.nlm.nih.gov/pubmed/23166521
http://dx.doi.org/10.1371/journal.pgen.1003078