A Unified Method for Detecting Secondary Trait Associations with Rare Variants: Application to Sequence Data

Next-generation sequencing has made possible the detection of rare variant (RV) associations with quantitative traits (QT). Due to high sequencing cost, many studies can only sequence a modest number of selected samples with extreme QT. Therefore association testing in individual studies can be unde...

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Detalles Bibliográficos
Autores principales: Liu, Dajiang J., Leal, Suzanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499373/
https://www.ncbi.nlm.nih.gov/pubmed/23166519
http://dx.doi.org/10.1371/journal.pgen.1003075

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