Affinity Is an Important Determinant of the Anti-Trypanosome Activity of Nanobodies

BACKGROUND: The discovery of Nanobodies (Nbs) with a direct toxic activity against African trypanosomes is a recent advancement towards a new strategy against these extracellular parasites. The anti-trypanosomal activity relies on perturbing the highly active recycling of the Variant-specific Surfac...

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Detalles Bibliográficos
Autores principales: Caljon, Guy, Stijlemans, Benoît, Saerens, Dirk, Van Den Abbeele, Jan, Muyldermans, Serge, Magez, Stefan, De Baetselier, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499403/
https://www.ncbi.nlm.nih.gov/pubmed/23166849
http://dx.doi.org/10.1371/journal.pntd.0001902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499403/
https://www.ncbi.nlm.nih.gov/pubmed/23166849
http://dx.doi.org/10.1371/journal.pntd.0001902

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