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Affinity Is an Important Determinant of the Anti-Trypanosome Activity of Nanobodies
BACKGROUND: The discovery of Nanobodies (Nbs) with a direct toxic activity against African trypanosomes is a recent advancement towards a new strategy against these extracellular parasites. The anti-trypanosomal activity relies on perturbing the highly active recycling of the Variant-specific Surfac...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499403/ https://www.ncbi.nlm.nih.gov/pubmed/23166849 http://dx.doi.org/10.1371/journal.pntd.0001902 |