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The Human Cytomegalovirus DNA Polymerase Processivity Factor UL44 Is Modified by SUMO in a DNA-Dependent Manner

During the replication of human cytomegalovirus (HCMV) genome, the viral DNA polymerase subunit UL44 plays a key role, as by binding both DNA and the polymerase catalytic subunit it confers processivity to the holoenzyme. However, several lines of evidence suggest that UL44 might have additional rol...

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Detalles Bibliográficos
Autores principales: Sinigalia, Elisa, Alvisi, Gualtiero, Segré, Chiara V., Mercorelli, Beatrice, Muratore, Giulia, Winkler, Michael, Hsiao, He-Hsuan, Urlaub, Henning, Ripalti, Alessandro, Chiocca, Susanna, Palù, Giorgio, Loregian, Arianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499415/
https://www.ncbi.nlm.nih.gov/pubmed/23166733
http://dx.doi.org/10.1371/journal.pone.0049630