Induction of Protective Anti-CTL Epitope Responses against HER-2-Positive Breast Cancer Based on Multivalent T7 Phage Nanoparticles

We report here the development of multivalent T7 bacteriophage nanoparticles displaying an immunodominant H-2k(d)-restricted CTL epitope derived from the rat HER2/neu oncoprotein. The immunotherapeutic potential of the chimeric T7 nanoparticles as anti-cancer vaccine was investigated in BALB/c mice...

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Detalles Bibliográficos
Autores principales: Pouyanfard, Somayeh, Bamdad, Taravat, Hashemi, Hamidreza, Bandehpour, Mojgan, Kazemi, Bahram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499470/
https://www.ncbi.nlm.nih.gov/pubmed/23166703
http://dx.doi.org/10.1371/journal.pone.0049539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499470/
https://www.ncbi.nlm.nih.gov/pubmed/23166703
http://dx.doi.org/10.1371/journal.pone.0049539

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