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Nucleolar Protein Trafficking in Response to HIV-1 Tat: Rewiring the Nucleolus

The trans-activator Tat protein is a viral regulatory protein essential for HIV-1 replication. Tat trafficks to the nucleoplasm and the nucleolus. The nucleolus, a highly dynamic and structured membrane-less sub-nuclear compartment, is the site of rRNA and ribosome biogenesis and is involved in nume...

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Detalles Bibliográficos
Autores principales: Jarboui, Mohamed Ali, Bidoia, Carlo, Woods, Elena, Roe, Barbara, Wynne, Kieran, Elia, Giuliano, Hall, William W., Gautier, Virginie W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499507/
https://www.ncbi.nlm.nih.gov/pubmed/23166591
http://dx.doi.org/10.1371/journal.pone.0048702