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HMGA1 Reprograms Somatic Cells into Pluripotent Stem Cells by Inducing Stem Cell Transcriptional Networks

BACKGROUND: Although recent studies have identified genes expressed in human embryonic stem cells (hESCs) that induce pluripotency, the molecular underpinnings of normal stem cell function remain poorly understood. The high mobility group A1 (HMGA1) gene is highly expressed in hESCs and poorly diffe...

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Detalles Bibliográficos
Autores principales: Shah, Sandeep N., Kerr, Candace, Cope, Leslie, Zambidis, Elias, Liu, Cyndi, Hillion, Joelle, Belton, Amy, Huso, David L., Resar, Linda M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499526/
https://www.ncbi.nlm.nih.gov/pubmed/23166588
http://dx.doi.org/10.1371/journal.pone.0048533