Expression Levels of the ABCG2 Multidrug Transporter in Human Erythrocytes Correspond to Pharmacologically Relevant Genetic Variations

We have developed a rapid, simple and reliable, antibody-based flow cytometry assay for the quantitative determination of membrane proteins in human erythrocytes. Our method reveals significant differences between the expression levels of the wild-type ABCG2 protein and the heterozygous Q141K polymo...

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Detalles Bibliográficos
Autores principales: Kasza, Ildikó, Várady, György, Andrikovics, Hajnalka, Koszarska, Magdalena, Tordai, Attila, Scheffer, George L., Németh, Adrienn, Szakács, Gergely, Sarkadi, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499528/
https://www.ncbi.nlm.nih.gov/pubmed/23166586
http://dx.doi.org/10.1371/journal.pone.0048423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499528/
https://www.ncbi.nlm.nih.gov/pubmed/23166586
http://dx.doi.org/10.1371/journal.pone.0048423

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