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Expression Levels of the ABCG2 Multidrug Transporter in Human Erythrocytes Correspond to Pharmacologically Relevant Genetic Variations
We have developed a rapid, simple and reliable, antibody-based flow cytometry assay for the quantitative determination of membrane proteins in human erythrocytes. Our method reveals significant differences between the expression levels of the wild-type ABCG2 protein and the heterozygous Q141K polymo...
Autores principales: | Kasza, Ildikó, Várady, György, Andrikovics, Hajnalka, Koszarska, Magdalena, Tordai, Attila, Scheffer, George L., Németh, Adrienn, Szakács, Gergely, Sarkadi, Balázs |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499528/ https://www.ncbi.nlm.nih.gov/pubmed/23166586 http://dx.doi.org/10.1371/journal.pone.0048423 |
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