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Role of Human Sec63 in Modulating the Steady-State Levels of Multi-Spanning Membrane Proteins

The Sec61 translocon of the endoplasmic reticulum (ER) membrane forms an aqueous pore, allowing polypeptides to be transferred across or integrated into membranes. Protein translocation into the ER can occur co- and posttranslationally. In yeast, posttranslational translocation involves the heptamer...

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Detalles Bibliográficos
Autores principales: Mades, Andreas, Gotthardt, Katherina, Awe, Karin, Stieler, Jens, Döring, Tatjana, Füser, Sabine, Prange, Reinhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499540/
https://www.ncbi.nlm.nih.gov/pubmed/23166619
http://dx.doi.org/10.1371/journal.pone.0049243