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Role of Human Sec63 in Modulating the Steady-State Levels of Multi-Spanning Membrane Proteins
The Sec61 translocon of the endoplasmic reticulum (ER) membrane forms an aqueous pore, allowing polypeptides to be transferred across or integrated into membranes. Protein translocation into the ER can occur co- and posttranslationally. In yeast, posttranslational translocation involves the heptamer...
Autores principales: | Mades, Andreas, Gotthardt, Katherina, Awe, Karin, Stieler, Jens, Döring, Tatjana, Füser, Sabine, Prange, Reinhild |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499540/ https://www.ncbi.nlm.nih.gov/pubmed/23166619 http://dx.doi.org/10.1371/journal.pone.0049243 |
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