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In Vitro and Ex Vivo Inhibition of Human Telomerase by Anti-HIV Nucleoside Reverse Transcriptase Inhibitors (NRTIs) but Not by Non-NRTIs

Telomerase is a specialized reverse transcriptase responsible for the de novo synthesis of telomeric DNA repeats. In addition to its established reverse transcriptase and terminal transferase activities, recent reports have revealed unexpected cellular activities of telomerase, including RNA-depende...

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Detalles Bibliográficos
Autores principales: Hukezalie, Kyle R., Thumati, Naresh R., Côté, Hélène C. F., Wong, Judy M. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499584/
https://www.ncbi.nlm.nih.gov/pubmed/23166583
http://dx.doi.org/10.1371/journal.pone.0047505