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In Vitro and Ex Vivo Inhibition of Human Telomerase by Anti-HIV Nucleoside Reverse Transcriptase Inhibitors (NRTIs) but Not by Non-NRTIs
Telomerase is a specialized reverse transcriptase responsible for the de novo synthesis of telomeric DNA repeats. In addition to its established reverse transcriptase and terminal transferase activities, recent reports have revealed unexpected cellular activities of telomerase, including RNA-depende...
Autores principales: | Hukezalie, Kyle R., Thumati, Naresh R., Côté, Hélène C. F., Wong, Judy M. Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499584/ https://www.ncbi.nlm.nih.gov/pubmed/23166583 http://dx.doi.org/10.1371/journal.pone.0047505 |
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