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A vaccine strategy protects against genital herpes by establishing local memory T cells

The majority of successful existing vaccines rely on neutralizing antibodies, which may not require specific anatomical localization of B cells. However, efficacious vaccines that rely on T cells for protection have been difficult to develop, as robust systemic memory T cell responses do not necessa...

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Detalles Bibliográficos
Autores principales: Shin, Haina, Iwasaki, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499630/
https://www.ncbi.nlm.nih.gov/pubmed/23075848
http://dx.doi.org/10.1038/nature11522