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Janus-faced role of SIRT1 in tumorigenesis
Silent mating type information regulation 1 (Sirtuin 1; SIRT1) has been reported to regulate various physiological events, such as aging and metabolism, via deacetylation of histone and nonhistone proteins. Notably, cumulative evidence supports the notion that SIRT1 has a Janus-faced role in tumorig...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Inc
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499659/ https://www.ncbi.nlm.nih.gov/pubmed/23050959 http://dx.doi.org/10.1111/j.1749-6632.2012.06762.x |