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Purine nucleosides: endogenous neuroprotectants in hypoxic brain

ABSTRACT: Even a short blockade of oxygen flow in brain may lead to the inhibition of oxidative phosphorylation and depletion of cellular ATP, which results in profound deficiencies in cellular function. Following ischemia, dying, injured, and hypoxic cells release soluble purine-nucleotide and -nuc...

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Detalles Bibliográficos
Autores principales: Thauerer, Bettina, zur Nedden, Stephanie, Baier-Bitterlich, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499684/
https://www.ncbi.nlm.nih.gov/pubmed/22335456
http://dx.doi.org/10.1111/j.1471-4159.2012.07692.x