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Prevention of lethal murine pancreas ischemia reperfusion injury is specific for tetrahydrobiopterin

Tetrahydrobiopterin has been shown to efficiently abrogate ischemia reperfusion injury (IRI). However, it is unclear, whether its beneficial action relies on cofactor activity of one of the five known tetrahydrobiopterin-dependent reactions or on its antioxidative capacity. We therefore compared tet...

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Detalles Bibliográficos
Autores principales: Maglione, Manuel, Cardini, Benno, Oberhuber, Rupert, Watschinger, Katrin, Jenny, Marcel, Gostner, Johanna, Hermann, Martin, Obrist, Peter, Margreiter, Raimund, Pratschke, Johann, Brandacher, Gerald, Werner, Ernst R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499685/
https://www.ncbi.nlm.nih.gov/pubmed/22805419
http://dx.doi.org/10.1111/j.1432-2277.2012.01530.x