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New perspectives on the ligands and function of the killer cell immunoglobulin-like receptor KIR3DL2 in health and disease

KIR3DL2/CD158k/p140 is a three domain killer cell immunoglobulin-like receptor incorporating cytoplasmic immunoreceptor tyrosine inhibitory motifs, expressed as a disulphide-bonded dimer. KIR3DL2 is a framework gene within the KIR locus and is highly polymorphic, with 62 allelic variants possibly co...

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Detalles Bibliográficos
Autores principales: Shaw, Jacqueline, Kollnberger, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499701/
https://www.ncbi.nlm.nih.gov/pubmed/23162554
http://dx.doi.org/10.3389/fimmu.2012.00339