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Does Lin28 Antagonize miRNA-Mediated Repression by Displacing miRISC from Target mRNAs?

Lin28 is a developmentally regulated RNA-binding protein that plays important roles in diverse physiological and pathological processes including oncogenesis and brain synaptic function. These pleiotropic roles of Lin28 are mechanistically linked both to its ability to directly stimulate translation...

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Detalles Bibliográficos
Autores principales: Kallen, Amanda N., Ma, Jing, Huang, Yingqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499807/
https://www.ncbi.nlm.nih.gov/pubmed/23162570
http://dx.doi.org/10.3389/fgene.2012.00240