Cargando…

Human Leukocyte Antigen (HLA) Class I Down-Regulation by Human Immunodeficiency Virus Type 1 Negative Factor (HIV-1 Nef): What Might We Learn From Natural Sequence Variants?

HIV-1 causes a chronic infection in humans that is characterized by high plasma viremia, progressive loss of CD4+ T lymphocytes, and severe immunodeficiency resulting in opportunistic disease and AIDS. Viral persistence is mediated in part by the ability of the Nef protein to down-regulate HLA molec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mwimanzi, Philip, Markle, Tristan J., Ueno, Takamasa, Brockman, Mark A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499827/ https://www.ncbi.nlm.nih.gov/pubmed/23170180 http://dx.doi.org/10.3390/v4091711

Ejemplares similares

Brockman, M.A., et al., Human Leukocyte Antigen (HLA) Class I Down-Regulation by Human Immunodeficiency Virus Type 1 Negative Factor (HIV-1 Nef): What Might We Learn From Natural Sequence Variants? Viruses 2012, 4, 1711-1730
por: Mwimanzi, Philip, et al.
Publicado: (2012)

Naturally-arising amino acid polymorphisms of HIV-1 Nef that differentially modulate downregulation of HLA-A and HLA-B molecules
por: Mahiti, Macdonald, et al.
Publicado: (2013)

Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences
por: Mahiti, Macdonald, et al.
Publicado: (2016)

Attenuation of multiple Nef functions in HIV-1 elite controllers
por: Mwimanzi, Philip, et al.
Publicado: (2013)

Impairment of viral replication capacity by nef alleles from HIV elite controllers
por: Mwimanzi, Philip, et al.
Publicado: (2011)

Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nef's functionality in primary macrophages
por: Mwimanzi, Philip, et al.
Publicado: (2011)

Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes
por: Mann, Jaclyn K, et al.
Publicado: (2013)

Modelling and in vitro testing of the HIV-1 Nef fitness landscape
por: Barton, John P, et al.
Publicado: (2019)

The Identification of a Small Molecule Compound That Reduces HIV-1 Nef-Mediated Viral Infectivity Enhancement
por: Chutiwitoonchai, Nopporn, et al.
Publicado: (2011)

HIV-1 subtype C Nef-mediated SERINC5 down-regulation significantly contributes to overall Nef activity
por: Naicker, Delon, et al.
Publicado: (2023)

Genetic determinants of Nef-mediated CD4 and HLA class I down-regulation differences between HIV-1 subtypes B and C
por: Mann, Jaclyn K., et al.
Publicado: (2015)

Natural HIV-1 Nef Polymorphisms Impair SERINC5 Downregulation Activity
por: Jin, Steven W., et al.
Publicado: (2019)

Severe immunodeficiency associated with a human immunodeficiency virus 1 NEF/3'-long terminal repeat transgene
Publicado: (1994)

Human Leukocyte Antigen (HLA) class I and II datasets for sudanese
por: Dafalla, Ameer Mohamed, et al.
Publicado: (2019)

Allele-Independent Turnover of Human Leukocyte Antigen (HLA) Class Ia Molecules
por: Prevosto, Claudia, et al.
Publicado: (2016)

CD8(+) T Cell Cross-Reactivity Profiles and HIV-1 Immune Escape towards an HLA-B35-Restricted Immunodominant Nef Epitope
por: Motozono, Chihiro, et al.
Publicado: (2013)

Human Immunodeficiency Virus Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration
por: Campbell, Grant R., et al.
Publicado: (2015)

Down-Regulation of CTLA-4 by HIV-1 Nef Protein
por: El-Far, Mohamed, et al.
Publicado: (2013)

HLA-Associated Immune Escape Pathways in HIV-1 Subtype B Gag, Pol and Nef Proteins
por: Brumme, Zabrina L., et al.
Publicado: (2009)

Cell Surface B2m-Free Human Leukocyte Antigen (HLA) Monomers and Dimers: Are They Neo-HLA Class and Proto-HLA?
por: Ravindranath, Mepur H., et al.
Publicado: (2023)

Endo-lysosomal assembly variations among human leukocyte antigen class I (HLA class I) allotypes
por: Olson, Eli, et al.
Publicado: (2023)

Attenuated HIV-1 Nef But Not Vpu Function in a Cohort of Rwandan Long-Term Survivors
por: Umviligihozo, Gisele, et al.
Publicado: (2022)

Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Human and Simian Immunodeficiency Viruses
por: McNamara, Ryan P., et al.
Publicado: (2018)

Implications of HIV-1 Nef for “Shock and Kill” Strategies to Eliminate Latent Viral Reservoirs
por: Kuang, Xiaomei T., et al.
Publicado: (2018)

Importance of Human Leukocyte Antigen (HLA) Class I and II Alleles on the Risk of Multiple Sclerosis
por: Link, Jenny, et al.
Publicado: (2012)

Association of Human Leukocyte Antigen (HLA) class II (DRB1 and DQB1) alleles and haplotypes with Rheumatoid Arthritis in Sudanese patients
por: Ali, Adil Ahmed, et al.
Publicado: (2023)

Chemotactic activity of HIV-1 Nef for human monocytes
por: Lehmann, MH, et al.
Publicado: (2006)

HIV-1 Nef blocks autophagy in human astrocytes
por: Sardo, Luca, et al.
Publicado: (2015)

Human Immunodeficiency Virus Type 1 Nef protein modulates the lipid composition of virions and host cell membrane microdomains
por: Brügger, Britta, et al.
Publicado: (2007)

The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes
Publicado: (1994)

Melanoma and Human Leukocyte Antigen (HLA): Immunogenicity of 69 HLA Class I Alleles With 11 Antigens Expressed in Melanoma Tumors
por: Georgopoulos, Apostolos P, et al.
Publicado: (2023)

Evolution of the HIV-1 nef gene in HLA-B*57 Positive Elite Suppressors
por: Salgado, Maria, et al.
Publicado: (2010)

Evolution and Diversity of the Human Leukocyte Antigen(HLA)
por: Markov, Peter V., et al.
Publicado: (2015)

Classification of Human Leukocyte Antigen (HLA) Supertypes
por: Wang, Mingjun, et al.
Publicado: (2014)

Human leukocyte antigen (HLA) class I frequencies in human T-cell lymphotropic virus type 1 (HTLV-1)-infected patients from Salvador-Brazil
por: Olavarria, Viviana N, et al.
Publicado: (2011)

Relationship between human leukocyte antigen (HLA)-DQA1*0102/HLA-DQB1*0602 polymorphism and preeclampsia
por: Mohammadi, Mahmoud, et al.
Publicado: (2017)

Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5
por: Jin, Steven W., et al.
Publicado: (2020)

Class II Human Leukocyte Antigen (HLA) and Susceptibility to Polypoidal Choroidal Vasculopathy in Afro-Caribbean Descent
por: Merle, Harold, et al.
Publicado: (2022)

Immunization of mice with the nef gene from Human Immunodeficiency Virus type 1: Study of immunological memory and long-term toxicology
por: Bråve, Andreas, et al.
Publicado: (2007)

The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages
Publicado: (1994)

Cannot write session to /tmp/vufind_sessions/sess_cr4ba9jk2oqskibkpfkkficiuk