Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma

Polyamines are highly regulated essential cations that are elevated in rapidly proliferating tissues, including diverse cancers. Expression analyses in neuroblastomas suggest that up-regulation of polyamine pro-synthetic enzymes and down-regulation of catabolic enzymes is associated with poor progno...

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Detalles Bibliográficos
Autores principales: Gamble, Laura D., Hogarty, Michael D., Liu, Xueyuan, Ziegler, David S., Marshall, Glenn, Norris, Murray D., Haber, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499881/
https://www.ncbi.nlm.nih.gov/pubmed/23181218
http://dx.doi.org/10.3389/fonc.2012.00162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499881/
https://www.ncbi.nlm.nih.gov/pubmed/23181218
http://dx.doi.org/10.3389/fonc.2012.00162

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