Cargando…
Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma
Polyamines are highly regulated essential cations that are elevated in rapidly proliferating tissues, including diverse cancers. Expression analyses in neuroblastomas suggest that up-regulation of polyamine pro-synthetic enzymes and down-regulation of catabolic enzymes is associated with poor progno...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499881/ https://www.ncbi.nlm.nih.gov/pubmed/23181218 http://dx.doi.org/10.3389/fonc.2012.00162 |