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Novel Agents and Emerging Strategies for Targeting the B-Cell Receptor Pathway in CLL

Chronic lymphocytic leukemia (CLL) is a disease of malignant CD5+ B lymphocytes that are characterized by frequent expression of autoreactive B-cell receptors (BCRs) and marked dependence on microenvironmental signals for proliferation and survival. Among the latter, signals propagated through the B...

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Detalles Bibliográficos
Autores principales: Efremov, Dimitar G., Wiestner, Adrian, Laurenti, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499997/
https://www.ncbi.nlm.nih.gov/pubmed/23170196
http://dx.doi.org/10.4084/MJHID.2012.067