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Novel Agents and Emerging Strategies for Targeting the B-Cell Receptor Pathway in CLL
Chronic lymphocytic leukemia (CLL) is a disease of malignant CD5+ B lymphocytes that are characterized by frequent expression of autoreactive B-cell receptors (BCRs) and marked dependence on microenvironmental signals for proliferation and survival. Among the latter, signals propagated through the B...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Università Cattolica del Sacro Cuore
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499997/ https://www.ncbi.nlm.nih.gov/pubmed/23170196 http://dx.doi.org/10.4084/MJHID.2012.067 |