Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction

AIMS: Increasing energy storage capacity by elevating creatine and phosphocreatine (PCr) levels to increase ATP availability is an attractive concept for protecting against ischaemia and heart failure. However, testing this hypothesis has not been possible since oral creatine supplementation is inef...

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Detalles Bibliográficos
Autores principales: Lygate, Craig A., Bohl, Steffen, ten Hove, Michiel, Faller, Kiterie M.E., Ostrowski, Philip J., Zervou, Sevasti, Medway, Debra J., Aksentijevic, Dunja, Sebag-Montefiore, Liam, Wallis, Julie, Clarke, Kieran, Watkins, Hugh, Schneider, Jürgen E., Neubauer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500046/
https://www.ncbi.nlm.nih.gov/pubmed/22915766
http://dx.doi.org/10.1093/cvr/cvs272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500046/
https://www.ncbi.nlm.nih.gov/pubmed/22915766
http://dx.doi.org/10.1093/cvr/cvs272

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