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Disseminated Breast Cancer Cells Acquire a Highly Malignant and Aggressive Metastatic Phenotype during Metastatic Latency in the Bone
BACKGROUND: Disseminated tumor cells (DTCs) in the bone marrow may exist in a dormant state for extended periods of time, maintaining the ability to proliferate upon activation, engraft at new sites, and form detectable metastases. However, understanding of the behavior and biology of dormant breast...
Autores principales: | Marsden, Carolyn G., Wright, Mary Jo, Carrier, Latonya, Moroz, Krzysztof, Rowan, Brian G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500091/ https://www.ncbi.nlm.nih.gov/pubmed/23173031 http://dx.doi.org/10.1371/journal.pone.0047587 |
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