Cargando…

Functional nsSNPs from carcinogenesis-related genes expressed in breast tissue: Potential breast cancer risk alleles and their distribution across human populations

Although highly penetrant alleles of BRCA1 and BRCA2 have been shown to predispose to breast cancer, the majority of breast cancer cases are assumed to result from the presence of low-moderate penetrant alleles and environmental carcinogens. Non-synonymous single nucleotide polymorphisms (nsSNPs) ar...

Descripción completa

Detalles Bibliográficos
Autores principales: Savas, Sevtap, Schmidt, Steffen, Jarjanazi, Hamdi, Ozcelik, Hilmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500178/
https://www.ncbi.nlm.nih.gov/pubmed/16595073
http://dx.doi.org/10.1186/1479-7364-2-5-287