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Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels

Association studies are used to identify genetic determinants of complex human traits of medical interest. With the large number of validated single nucleotide polymorphisms (SNPs) currently available, two limiting factors in association studies are genotyping capability and costs. Pooled DNA genoty...

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Detalles Bibliográficos
Autores principales: Hinds, David A, Seymour, Albert B, Durham, L Kathryn, Banerjee, Poulabi, Ballinger, Dennis G, Milos, Patrice M, Cox, David R, Thompson, John F, Frazer, Kelly A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500196/
https://www.ncbi.nlm.nih.gov/pubmed/15606997
http://dx.doi.org/10.1186/1479-7364-1-6-421